[JACS] Photodynamic and Photothermal Effects of Semiconducting and Metallic-Enriched Single-Walled Carbon Nanotubes
19 October 2012
[Journal of the American Chemical Society (JACS)] Semiconducting and metallic single-walled carbon nanotubes (s-SWNTs and m-SWNTs) were enriched by agarose gel chromatography and their photothermal and photodynamic effects were compared in H2O. The Tatsuya Murakami and Hiroshi Imahori labs, and their colleagues at Kyoto University have demonstrated that under near-infrared laser irradiation, s-SWNTs generated reactive oxygen species (ROS) more than m-SWNTs, whereas m-SWNTs produced heat more efficiently than s-SWNTs. More importantly, cancer cell killing by PDE of s-SWNTs has been disclosed for the first time. [
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These findings have received nationwide media coverage in Japan.
Publication information
Photodynamic and Photothermal Effects of Semiconducting and Metallic-Enriched Single-Walled Carbon Nanotubes
Tatsuya Murakami*, Hirotaka Nakatsuji, Mami Inada, Yoshinori Matoba, Tomokazu Umeyama, Masahiko Tsujimoto, Seiji Isoda, Mitsuru Hashida, Hiroshi Imahori*
Journal of the American Chemical Society (JACS) | Published online 19 October 2012 | DOI: 10.1021/ja3079972