4th iCeMS Seminar - Dr. Ira Pastan

On Wednesday, April 23, Dr. Ira Pastan from NIH will give an iCeMS seminar, entitled "Immunotoxins in 2008: Successes and Challenges: Effective Treatment of Drug Resistant Hairy Cell Leukemia by Immunotoxin BL22."

Most cancers cannot be cured once they have metastasized. To develop a new treatment for metastatic cancer, Dr. Pastan and his team have used genetic engineering to modify a powerful bacterial toxin, Pseudomonas exotoxin A (PE), so that instead of killing normal cells it selectively kills cancer cells. PE-based anti-cancer agents have been produced by replacing the binding domain of PE with the Fv fragment of an antibody or with a growth factor that binds to cancer cells. These agents are termed "recombinant immunotoxins". They are currently conducting clinical trials with some of these immunotoxins. In this presentation, Dr. Pastan will present his recent progress of the clinical applications of BL22, which targets CD22 on B cell leukemias and lymphomas.

Lecturer	Dr. Ira Pastan Head, Molecular Biology Section Chief, Laboratory of Molecular Biology, Center for Cancer Research National Cancer Institute, National Institutes of Health, U. S. A.
Title	Immunotoxins in 2008: Successes and Challenges: Effective Treatment of Drug Resistant Hairy Cell Leukemia by Immunotoxin BL22
Moderator	Dr. Kazumitsu Ueda Professor of iCeMS and Faculty/Graduate School of Agriculture Kyoto University
Date/Time	Wednesday, April 23, 2008 / 16:00-17:00
Venue	Roof Terrace Institute for Frontier Medical Sciences, 5F of the East Building (140 KB)
Flyer	PDF (99 KB)
Contact	Aki Kusumi at akusumi@frontier.kyoto-u.ac.jp Fax: 751-4113
Held by	iCeMS (Institute for Integrated Cell-Material Sciences), Faculty / Graduate School of Agriculture The Institute for Frontier Medical Sciences, Kyoto University
Co-held by	Japan Society for Bioscience, Biotechnology, and Agrochemistry