131st iCeMS Seminar/CeMI Seminar Series 35: Prof. Pietro De Camilli

Endocytosis plays a fundamental role in all cells and a highly specialized role at neuronal synapses, where it mediates the recycling of synaptic vesicle membranes. Dr. De Camilli and his colleagues have capitalized on this highly specialized system to advance knowledge of fundamental mechanisms in endocytic membrane traffic. Dr. De Camilli will discuss how membrane deformation at endocytic sites is coupled, via adaptor proteins with curvature generating/sensing properties, to metabolic changes of phosphoinositides in the membrane bilayer and will address more generally the importance of these phospholipids in the control of membrane dynamics and interactions.

Lecturer
Prof. Pietro De Camilli
Department of Cell Biology, Howard Hughes Medical Institute
Program in Cellular Neuroscience Neurodegeneration and Repair, Kavli Institute for Neuroscience
Yale University School of Medicine, USA
Title Membrane Dynamics and Phosphoinositide Signaling in the Endocytic Pathway
Date / Time Tuesday, February 5, 2013 / 10:30-11:30
Venue 2nd Floor Seminar Room (#A207), iCeMS Main Building (#71), Kyoto University
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Host Kyoto University Institute for Integrated Cell-Material Sciences (WPI-iCeMS)
Co-host Kyoto University's Global COE Program: Center for Frontier Medicine
Contact iCeMS Heuser Lab | heuser-g@icems.kyoto-u.ac.jp
iCeMS Kusumi Lab | kusumi-g@icems.kyoto-u.ac.jp