164th iCeMS Seminar/CeMI Seminar Series 42: Assoc. Prof. Radu V. Stan
CeMI：Center for Meso-Bio Single-Molecule Imaging
Vascular permeability is a vital cardiovascular function by which endothelial cells, lining the entire cardiovascular system, mediate the exchange of myriad molecules between the blood plasma and the interstitial fluid of all tissues and organs of vertebrates to mammals. Fenestral and stomatal diaphragms are endothelial subcellular structures that form on organelles implicated in vascular permeability: fenestrae, transendothelial channels and caveolae. Prof. Stan's group found that PV1 protein is required for diaphragm formation and barrier function. Their data provide genetic evidence for the important role of the diaphragms in basal permeability of fenestrated capillaries and the maintenance of blood homeostasis.
| Lecturer |  Dept of Pathology, Dartmouth Medical School The Geisel School of Medicine at Dartmouth College |
|---|---|
| Title | The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood homeostasis |
| Date / Time | Tue 15 Apr 2014 / 11:00-12:00 |
| Venue | 2nd Floor Seminar Room (#A207), iCeMS Main Building (#70), Kyoto University -> Directions |
| Flyer |  PDF (100KB) |
| Host | Kyoto University Institute for Integrated Cell-Material Sciences (WPI-iCeMS) | Contact | iCeMS Kusumi Group | kusumi-g@icems.kyoto-u.ac.jp |