183rd iCeMS Seminar/CeMI Seminar Series 44: Prof. Young-Tae Chang

CeMICenter for Meso-Bio Single-Molecule Imaging

The conventional bioprobe design has been carried out by so-called hypothesis-driven approach. The basic assumption of hypothesis-driven approach is that the scientist "knows the target" in advance, and then design the recognition motif for it. An alternative approach is diversity-driven approach, in which a broad range of fuorescence molecules in a library format are constructed by combinatorial chemistry, as a tool box for unbiased screening. Using the Diversity Oriented Fluorescence Library Approach (DOFLA), Dr. Chang and his colleagues developed various colorful sensors for many different analyses and bioimaging probes from stem cells to neuronal cells. Dr. Chang will present these results as well as the whole animal imaging data obtained by near infrared probes.

Lecturer
Young-Tae Chang, Ph.D.
Department of Chemistry
National University of Singapore
Title Universal fluorescent probe platform for almost everything
Date / Time Wed 15 April 2015 / 10:00-11:00
Venue 2nd Floor Seminar Room (#A207), iCeMS Main Building (#77), Kyoto University
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Flyer PDF FilePDF (91KB)
Host Kyoto University Institute for Integrated Cell-Material Sciences (WPI-iCeMS)
Contact iCeMS Kusumi Group | kusumi-g@icems.kyoto-u.ac.jp