- Research News
- July 19, 2017
Accessing DNA in the cell’s powerhouse to treat disease
A new molecule that reads mitochondrial DNA could pave the way to treat some genetic nerve and muscle diseases.
Most DNA is found in the nucleus. But mitochondria, the cell’s powerhouses, also host a small amount of DNA. Pyrrole-imidazole polyamides (PIPs) are capable of crossing the nuclear membrane to bind to nuclear DNA, but are incapable of crossing the mitochondrial membrane.
A team, led by Ganesh Pandian Namasivayam, from Kyoto University’s Institute for Integrated Cell-Material Science (iCeMS) succeeded to re-direct PIP to cross the mitochondrial membrane so that it can access its DNA and alter gene transcription.
Further details are available at the following page:
Kyoto University: Accessing DNA in the cell’s powerhouse to treat disease
Getting closer to porous, light-responsive materials
July 25, 2017
Killing cancer in the heat of the moment
July 11, 2017
Changing the color of laser light on the femtosecond time scale: How BiCoO3 achieves second harmonic generation
June 20, 2017