第11回 アイセムスセミナー：Peter W. Andrews 教授
A key feature of pluripotent stem cells is their ability to proliferate indefinitely
while maintaining an ability to differentiate into all somatic cell types. Such
proliferation is known as 'self-renewal'. However, these cells may also
differentiate spontaneously, or in response to specific cues. When they divide,
stem cells must choose between self renewal and commitment to differentiation.
Further, if they commit to differentiate they must choose between different
lineages. An understanding of the molecular mechanisms that control these
decision processes underlies any potential use of human embryonic stem (ES)
cells, or iPS cells, whether in regenerative medicine or in other areas such as drug
discovery, toxicology or disease modeling.
Selected References: Baker et al. (2007) Adaptation to culture of human embryonic stem cells and oncogenesis in vivo. Nature Biotechnology 25: 207 - 215.
| 講演者 | Prof. Peter W. Andrews, Ph.D. Centre for Stem Cell Biology and Department of Biomedical Science The University of Sheffield, UK |
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| 演題 | Population Dynamics of Human ES Cell Cultures: Self-Renewal, Adaptation and Cancer |
| 日時 | 2008年12月2日（火曜日） 13時00分-14時00分 |
| 場所 |  再生医科学研究所東館5階 ルーフテラス (PDF：140 KB) |
| フライヤー | PDF（英語）(122 KB) |
| 主催 | 京都大学 物質－細胞統合システム拠点（iCeMS＝アイセムス） 京都大学 再生医科学研究所 |
| 連絡先 | 中辻 憲夫 教授 電話：075-751-3808 |