第164回 アイセムスセミナー / CeMI セミナーシリーズ42: Radu V. Stan 准教授

CeMICenter for Meso-Bio Single-Molecule Imaging

Vascular permeability is a vital cardiovascular function by which endothelial cells, lining the entire cardiovascular system, mediate the exchange of myriad molecules between the blood plasma and the interstitial fluid of all tissues and organs of vertebrates to mammals. Fenestral and stomatal diaphragms are endothelial subcellular structures that form on organelles implicated in vascular permeability: fenestrae, transendothelial channels and caveolae. Prof. Stan's group found that PV1 protein is required for diaphragm formation and barrier function. Their data provide genetic evidence for the important role of the diaphragms in basal permeability of fenestrated capillaries and the maintenance of blood homeostasis.

講演者
Radu V Stan 准教授
Dept of Pathology, Dartmouth Medical School
The Geisel School of Medicine at Dartmouth College
演題 The diaphragms of fenestrated endothelia: gatekeepers of vascular permeability and blood homeostasis
日時 2014年4月15日(火)11:00-12:00
場所 京都大学 iCeMS 本館(#70)2階 セミナールーム (A207)
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フライヤー PDF FilePDF (100KB)
主催 京都大学 物質-細胞統合システム拠点(iCeMS=アイセムス)
連絡先 楠見グループ | kusumi-g@icems.kyoto-u.ac.jp