9th iCeMS Seminar - Assoc. Prof. Jack Taunton

Cells employ complex feedback circuits to polarize membrane and cytoskeletal components in response to extracellular cues.
Dr. Taunton's group has recently revealed two such feedback mechanisms for actin assembly and local membrane protrusion: (1) reversible, rate-limiting delivery of Cdc42 from its cytosolic chaperone, RhoGDI, to the membrane, and (2) direct binding of N-WASP to nascent actin filaments, resulting in an increased local density of N-WASP, and hence, of new actin filaments, near the plasma membrane.

Lecturer	Assoc. Prof. Jack Taunton Associate Professor Howard Hughes Medical Institute Department of Cellular and Molecular Pharmacology University of California, San Francisco
Title	Signal amplification by an actin-based diffusion trap
Date/Time	Monday, September 8, 2008 / 16:00-17:00 * Refreshments will be served from 15:40. Please come a little earlier before the seminar.
Venue	Roof Terrace Institute for Frontier Medical Sciences, 5F of the East Building (140 KB)
Flyer	PDF (101 KB)
Contact	Aki Kusumi at akusumi@frontier.kyoto-u.ac.jp Fax: 751-4113
Held by	iCeMS (Institute for Integrated Cell-Material Sciences), Kyoto University The Institute for Frontier Medical Sciences, Kyoto University Membrane Mechanisms Project, ICOPR-JST