97th iCeMS Seminar: Assoc. Prof. Shoji Takeuchi

In this presentation, I am planning to talk about several MEMS/Microfluidic-based approaches for the rapid and reproducible construction of biomaterials such as lipids, cells and hydrogels.

Fluorescent hydrogels hold great promise for in vivo continuous glucose monitoring with wireless transdermal transmission and long-lasting activity. We synthesized a highly-sensitive fluorescent monomer, and then fabricated injectable-sized fluorescent polyacrylamide hydrogel beads and fibers with high uniformity and high throughput. We find that the fluorescent beads provide sufficient intensity to transdermally monitor glucose concentrations in vivo.

Large-scale 3D tissue architectures that mimic microscopic tissue structures in vivo are very important for not only in tissue engineering but also drug development without animal experiments. We demonstrated a construction method of 3D tissue structures by stacking the "cellular beads" in a 3D mold. We believe that various 3D shapes can be possible by changing the mold, and this method is useful to create more complex structures with multiple types of cells that functions as a living organism.

Lecturer Title	Assoc. Prof. Shoji Takeuchi Center for International Research on Micronano Mechatronics (CIRMM) Institute of Industrial Science, The University of Tokyo Title: Microfluidic Assembly for Biomedical Applications
Date / Time	December 16, 2011 / 10:30-12:00
Venue	2nd floor Seminar Room (#A207), Main Building iCeMS Complex 1, Kyoto University Directions
Flyer	PDF (110KB)
Host	Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University
Co-Host	Center for Frontier Medicine, Global COE Program, Kyoto University
Contact	iCeMS Kitagawa Lab kitagawa-g@icems.kyoto-u.ac.jp