第153回 アイセムスセミナー: Takamune Saito 博士
Declining birth rates are a social problem in advanced nations. Infertility is one of its causes. Nowadays, approximately 15% of couples are suffering from infertility, therefore there is tremendous urgency in performing investigations to determine the causes and establish treatments for infertility. Meiosis is a special type of cell division that generates eggs and sperm resulting in halving of the chromosome number. Especially, crossover recombination between homologous chromosomes is essential for meiosis. Failure to successfully complete crossover recombination leads to genomic instability and aneuploidy, resulting in infertility, miscarriages and infant cancer in newborns. In this seminar, I will introduce the mechanisms of recombination focusing on the "Shuriken"-like multinuclease complex discovered by us and discuss its unexpected aspects.
| 講演者 |  Department of Genetics Harvard Medical School |
|---|---|
| 演題 | "Shuriken" prevents infertility: Genomic integrity in germ cells |
| 日時 | 2013年12月12日（木）14:00-15:00 |
| 場所 | 京都大学 iCeMS 研究棟1号館・プロジェクトラボ119号室 →アクセスマップ |
| フライヤー |  PDF (91KB) |
| 主催 | 京都大学 物質－細胞統合システム拠点（iCeMS＝アイセムス） |
| 連絡先 | iCeMS カールトングループ | carlton-g@icems.kyoto-u.ac.jp |