第157回 アイセムスセミナー: Jonathan Sleeman 教授
The reception and integration of the plethora of signals a cell receives from its microenvironment is decisive in determining cell behaviour. External signals that regulate cell behaviour and properties include signalling molecules such as growth factors and cytokines, extra cellular matrix (ECM) components, contacts with other cells, mechanical stress, the redox status of the surrounding milieu, and the local oxygen tension. Perturbation of extracellular cues or an inappropriate response or integration of these signals lies at the root of many diseases such as cancer. Accordingly it is increasingly recognised that changes in the extracellular environment can drive tumorigenesis, tumor progression and metastasis, and can act dominantly for example over genetic abberations in the tumor cells. In this talk I will discuss some of our recent findings about how the microenvironment regulates tumor metastasis.
| 講演者 |  Medical Faculty Mannheim University of Heidelberg |
|---|---|
| 演題 | Microenvironmental regulation of tumor metastasis |
| 日時 | 2014年3月19日（水）15:00-17:00 |
| 場所 | 京都大学 iCeMS 本館（#70）2階 セミナールーム (A207) -> アクセプマップ |
| フライヤー |  PDF (316KB) |
| 主催 | 京都大学 物質－細胞統合システム拠点（iCeMS＝アイセムス） | 連絡先 | 田中求グループ | mtanaka-g@icems.kyoto-u.ac.jp |