124th iCeMS Seminar/CeMI Seminar Series 34: Prof. Madan Rao, Prof. Antoine Triller

Prof. Madan Rao

Active cell surface organization and information processing

Dr. Madan Rao will discuss a model of an active composite cell surface wherein certain classes of cell surface molecules form dynamic nanoclusters as a consequence of being actively driven by cortical actomyosin. The active composite model makes several predictions which Dr. Rao's team verified using high resolution fluorescence methods. He will then discuss the consequences of this active composite model to the regulation and optimization of information processing.

Prof. Antoine Triller

From stochasticity of molecular processes to synapse stability and plasticity: toward chemistry in cellulo with microscopes

Dr. Triller has been investigating the issue of postsynaptic receptors dynamics, their interactions with scaffolding proteins, and regulations implicated in synaptic plasticity. Combination of single particle tracking and super-resolution methods has opened accesses to molecular counting and energy involved in receptor-scaffold interactions as well as on and off rate of molecular interactions. Thus beyond super-resolution methods is chemistry "in cellulo" accounting for the regulation of receptor number and consecutively that of synaptic strength. Dr. Triller will address these issues in his talk.

Lecturer	Prof. Madan Rao National Centre for Biological Sciences (NCBS) Bangalore, Karnataka, India Prof. Antoine Triller Ecole Normale Superieure and Institut National de la Santé de la Recherche Médicale (INSERM), France
Date / Time	November 19, 2012 / 10:00-12:00
Venue	2nd floor Seminar Room (#A207), Main Building iCeMS Complex 1, Kyoto University Directions
Flyer	PDF (185KB)
Host	Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University
Contact	iCeMS Kusumi Lab kusumi-g@icems.kyoto-u.ac.jp