iCeMS Suzuki Lab Seminar: Dr W.K. Eddie Ip

This notice is to inform you of an upcoming seminar, all researchers are welcomed to attend. No registration is required.

Dr W.K. Eddie Ip
Department of Immunology
College of Medicine, Mayo Clinic

Metabolic Reprogramming of Macrophages by IL-10
It is well appreciated that interleukin 10 (IL-10) is an anti-inflammatory cytokine that plays a critical role in the control of immune responses. However, its mechanisms of action remain largely unknown. In my seminar, I will discuss new mechanistic insight into the inhibitory effect of IL-10, and will specifically focus on how IL-10 inhibits inflammatory response in macrophages via controlling cellular metabolism. Moreover, I will discuss the relevance of our findings to inflammatory diseases in a mouse model of colitis and inflammatory bowel disease patients.