第214回iCeMSセミナー：Nicholas Graham 博士

Nicholas Graham 博士
Mork Family Dept. of Chemical Engineering and Materials Science, University of Southern California

Proteomic and metabolomic approaches to elucidate cell phenotypes
Many disease states including diabetes, inflammation and cancer involve dysregulation of signal transduction and metabolic pathways. Here, we will present our recent results demonstrating systems biology approaches using proteomics and metabolomics to understand cellular function, including how nucleotide metabolism determines replicative senescence of non-transformed cells and how DNA copy number alterations drive the metabolic phenotype of cancer cells.