Extracellular calcium gets into a pocket in the transmembrane region of scramblase, triggering the scramblase’s activation. This exposes phosphatidylserine (PS) on the cell surface, serving as a distinctive marker for the elimination of unwanted cells.
(Left) The ultrafast camera revealed molecules in the cell membrane (represented by various buddhas) appearing to dance within spaces bound by actin filaments (represented by the mandalas) and occasionally jumping over the boundaries. (Right) Pairing the ultrafast camera with SFMI allows the creation of pointillism-like images 60 times faster than previous methods.
Even without the symmetry and curvature of fullerenes, the designed flat fullerene fragments which maintained the pentagonal substructure displayed the same electron accepting properties as fullerenes.
The interaction between the small intestine and the liver of patients with non-alcoholic fatty liver disease (NAFLD) has been reproduced on a small chip.
Cholesterol transporter protein ABCA1 at the plasma membrane, and cholesterol transfer protein Aster-A at the endoplasmic reticulum membrane, function cooperatively to keep the amount of cholesterol (cargo) in the inner plasma membrane low.
Incorporating dragonfly-shaped gate molecules into PCP/MOFs makes it a hundred times more efficient than before to separate water from heavy water, which has been difficult to separate due to their similar properties.
Scientists found two new ways to identify substitutions from uracil to pseudouridine, combining existing sequencing technology with different approaches. One is with algorithm-based calculation, and one is with a chemical probe CMC.
The metal oxide clusters obtained in this study are positively (+) charged unlike conventional negatively (-) charged ones. Its surface protons are highly acidic, which is important in catalysis.
Exploration of a new structure for microfluidic devices. The image is an artistic rendering of the internal porous structure that is made using polymers and light. Researchers at iCeMS have achieved controlled liquid flow in this structure.
Researchers have produced iPS cells from the endangered Grévy’s zebra using human reprogramming factors, and found that those factors are evolutionarily conserved among animal species
This image offers an abstract visual representation of graphene oxide sheets (black layers) embedded with nanodiamonds (bright white points). The nanodiamonds exert long range electrostatic forces (nebulous white circles) which stabilize the sheets even in humid conditions creating a promising membrane material for hydrogen purification.
Yasuhiro Chida (Brocken 5) and Toru Tsuji (Photograph)
Original article: Zaoming Wang et al.
Multiscale structural control of linked metal–organic polyhedra gel by aging-induced linkage-reorganization
Chem. Sci. 2021, 12, 12556-12563.
Original article: Frederik Haase et al.
Pseudo-5-Fold Symmetrical Ligand Drives Geometric Frustration in Porous Metal-Organic and Hydrogen Bonded Frameworks
J. Am. Chem. Soc. 2020, 142, 13839–13845.
Original article: Alexandre Legrand et al.
Understanding the multiscale self-assembly of metal-organic polyhedra towards functionally graded porous gels
Chem Sci. 2019, 10, 10833-10842.
Original article: Arnau Carné-Sánchez et al.
Self-assembly of metal–organic polyhedra into supramolecular polymers with intrinsic microporosity
Nat. Commun. 2018, 9, 2506.
When X-rays are irradiated onto tumor tissue containing iodine-carrying nanoparticles, the iodine releases electrons that break DNA and kill the cancer cells.
